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Neuroscience

Glycine

Other name(s):

aminoacetic acid

Unsubstantiated claims

There may be benefits that have not yet been proven through research.

Glycine may help with ischemia-reperfusion injury.

It may also help protect the liver from toxins.

Glycine may help treat schizophrenia although not all study results are in agreement.

Recommended intake

Amino acids (AAs) can be taken as single AAs or in AA combinations. They also come as part of multivitamins, proteins, and food supplements. The forms include tablets, fluids, and powders.

If you eat enough protein in your diet, your body will get adequate levels of glycine.

There are no conditions that increase how much glycine you need.

Side effects, toxicity, and interactions

Using a single amino acid supplement may lead to negative nitrogen balance. This can lessen how well your metabolism works. It can also make your kidneys work harder. In children, taking single amino acid supplements may also cause growth problems. It may also cause seizures and developmental delays.

Don't take high doses of single amino acids for long periods of time.

Don't take high doses of single amino acids without talking with your healthcare provider.

Women who are pregnant or breastfeeding should not take glycine supplements.

Online Medical Reviewer: Amy Finke RN BSN
Online Medical Reviewer: Bianca Garilli MD
Online Medical Reviewer: Jessica Gotwals RN BSN MPH
Date Last Reviewed: 7/1/2023