Estradiol Vaginal Insert 4 mcg
For menopausal symptoms.
This medicine is for use in the vagina. DO NOT take this medicine by mouth.
Hold the insert with the larger end between your fingers and place it about 2 inches into the vagina.
Use the medicine at about the same time each day.
Keep the medicine at room temperature. Avoid heat and direct light.
Wash your hands before and after using this medicine.
This medicine may cause dark patches to appear on your face. Avoid sunlight and use sunscreen lotion to minimize further darkening of these skin patches.
Avoid prolonged or excessive sunlight exposure. Use sunscreen lotion with SPF 15 or higher.
If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal dosing schedule. Do not take 2 doses of this medicine at one time.
Please tell your doctor and pharmacist about all the medicines you take. Include both prescription and over-the-counter medicines. Also tell them about any vitamins, herbal medicines, or anything else you take for your health.
If your symptoms do not improve or they worsen while on this medicine, contact your doctor.
Do not share this medicine with anyone who has not been prescribed this medicine.
Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.
This medicine may increase the risk of some types of cancer in women. Please speak with your doctor about the risks and benefits of using this medicine.
This medicine is associated with an increased risk of serious heart problems, heart attack, and stroke. Please speak with your doctor about the risks and benefits of using this medicine. Contact your doctor immediately if you experience chest pain or difficulty breathing.
This medicine is associated with an increased risk for serious blood clots. Speak with your doctor about the benefits and risks from using this medicine.
Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine. Symptoms of an allergic reaction can include trouble breathing, skin rash, itching, swelling, or severe dizziness.
Do not use the medication any more than instructed.
Avoid smoking while on this medicine. Smoking may increase your risk for stroke, heart attack, blood clots, high blood pressure, and other diseases of the heart and blood vessels.
Ask your doctor to show you how to perform a self breast examination. You should check your breasts once a month and report any changes to your doctor.
Talk to your doctor about getting a complete physical exam every year while on this medicine.
Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.
Do not use this medicine if you are pregnant. If you become pregnant while on this medicine, contact your doctor immediately.
Ask your pharmacist if this medicine can interact with any of your other medicines. Be sure to tell them about all the medicines you take.
Please tell all your doctors and dentists that you are on this medicine before they provide care.
Do not start or stop any other medicines without first speaking to your doctor or pharmacist.
The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.
- breast pain or swelling
- brown colored patches on the face
- vaginal itching or discharge
- weight gain
Call your doctor or get medical help right away if you notice any of these more serious side effects:
- increased risk of a blood clot
- breast lumps
- chest pain
- depression or feeling sad
- swelling of the legs, feet, and hands
- severe or persistent headache
- jaw pain
- sudden leg pain, swelling, warmth or redness
- symptoms of liver damage (such as yellowing of skin or eyes, dark urine, unusual tiredness or weakness; severe stomach or back pain)
- shortness of breath
- symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
- persistent or unusual thirst
- increased urinary frequency
- cramping of the uterus or bleeding from the vagina
- vaginal itching or yeast infection
- sudden change or loss of vision
A few people may have an allergic reactions to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.
Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.
IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all
there is to know about it.Your doctor or pharmacist may give you other documents about your medicine.
Please talk to them if you have any questions.Always follow their advice. There is a more complete
description of this medicine available in English.Scan this code on your smartphone or tablet or use
the web address below. You can also ask your pharmacist for a printout. If you have
any questions, please ask your pharmacist.