Blood loss can happen if your child has an injury, surgery, or an illness that affects blood cells. Blood is made up of several different parts (blood products). Your child may receive some or all of these blood products through a transfusion. Blood for transfusion is donated from another person (donor). Strict measures are taken to make sure that donated blood is safe before it’s given to your child. Your child’s healthcare provider will discuss your child’s condition with you and answer your questions.
Blood can be separated into different parts that perform special roles in the body. These parts include:
Donors provide the blood used for transfusions. To make sure that blood is safe:
A child may need a blood transfusion during a planned surgery. Family and friends can have their blood tested for compatibility and donate blood for a child before the surgery. This needs to be done at least 7 day(s) in advance. This is because the blood must be tested for safety. Research has shown that blood directed by a family member is NOT safer than blood from the regular donor pool.
A blood transfusion takes place in a blood center, infusion center, hospital room, or operating room. Your child’s healthcare provider will discuss the blood transfusion with you before it’s done. You’ll need to give permission for the blood transfusion by signing a consent form:
Most transfusions are problem free. In some cases, reactions happen. These can happen within seconds or minutes during the transfusion or a week to a few months after the transfusion. The most common reactions from blood transfusions are mild allergic reaction and fever. Call the healthcare provider right away if your child has any of the following signs and symptoms during or after a transfusion:
Reaction
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Timing
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Signs and symptoms
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Allergic reaction (mild)
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Hives or red welts on the skin, mild itching, rash, localized swelling, flushing (red face), wheezing, shortness of breath, or stridor (high-pitched noise or sound)
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Anaphylactic reaction (severe allergic reaction)
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Shortness of breath, flushing (red face), wheezing, labored (working hard) breathing, low blood pressure, localized swelling, chest tightness, or cramps
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Febrile nonhemolytic reaction
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Fever, chills, flushing (red face), nausea, headache, minor discomfort, or mild shortness of breath
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Acute immune hemolytic reaction
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Fever, red or brown urine, back pain, fast heart rate (tachycardia), abdominal pain, low blood pressure, feeling anxious, chills, chest pain, nausea, or fainting spells
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Transfusion-related acute lung injury (TRALI)
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Shortness of breath, trouble breathing, low blood pressure, fever, pulmonary edema
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Transfusion-associated circulatory overload
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Shortness of breath, fast heart rate (tachycardia), problems breathing when lying on back, abnormal blood pressure
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Post-transfusion purpura (PUP)
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Purple spots on skin; nose bleed; bleeding from the urinary tract, abdomen, colon, or rectum; fever; or chills
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"Delayed" transfusion-related acute lung injury (TRALI)
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Sudden onset of respiratory distress or trouble breathing
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"Delayed" hemolytic reaction
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Low-grade fever, mild jaundice (yellowing of the skin and whites of the eyes), decrease in hematocrit, chills, chest pain, back pain, nausea
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